What type of drug is activase

Back Submit. Activase Cautionary Labels Back to Top. Uses of Activase Back to Top. Activase is a prescription medication used to treat: Acute myocardial infarction heart attack Acute ischemic stroke loss of blood flow to the brain Pulmonary embolism blood clot that has traveled to the lungs This medication may be prescribed for other uses.

Manufacturer Back to Top. Genentech, Inc. Generic Back to Top. Alteplase For more information on this medication choose from the list of selections below. Activase Drug Class Back to Top. Activase is part of the drug class: Antithrombotic Enzymes. Side Effects of Activase Back to Top.

Serious side effects have been reported with Activase. Activase Interactions Back to Top. Especially tell your doctor if you take: anticoagulant blood thinner medications such as warfarin Coumadin , Jantoven , heparin , enoxaparin Lovenox , fondaparinux Arixtra , rivaroxaban Xarelto , and apixaban Eliquis aspirin This is not a complete list of Activase drug interactions. Activase Precautions Back to Top. Serious side effects have been reported with Activase including the following: Bleeding.

Tell your healthcare provider right away if you have some or all of the following symptoms of bleeding. Activase Food Interactions Back to Top. Inform MD Back to Top. Activase and Pregnancy Back to Top. Tell your doctor if you are pregnant or plan to become pregnant. Activase and Lactation Back to Top. Tell your doctor if you are breastfeeding or plan to breastfeed. Activase Usage Back to Top. Take Activase exactly as prescribed. PE: mg infused over 2hrs.

Heparin may be used concomitantly in MI or after infusion in PE. Stroke: Intracranial or subarachnoid hemorrhage. All: Active internal bleeding.

Intracranial or intraspinal surgery or serious head trauma within 3 months. Intracranial neoplasm, arteriovenous malformation or aneurysm. Bleeding diathesis. Current severe uncontrolled hypertension.

Avoid IM inj and trauma to the patient while on therapy. Increased bleeding risk at puncture sites eg, arterial, internal jugular, subclavian venous ; avoid. N Engl J Med. FDA Access Summary basis of approval. Accessed August 14, Comprehensive overview of nursing and interdisciplinary care of the acute ischemic stroke patient: a scientific statement from the American Heart Association.

Guide to the Care of the Patient with Ischemic Stroke. Impact of stroke care unit on patient outcomes in a community hospital.

Centers for Medicare and Medicaid Services website. Published June 28, Accessed August 13, The Joint Commission, Stroke. Last updated June 17, Accessed August 1, Marked regional variation in acute stroke treatment among Medicare beneficiaries. Better health, less spending: delivery innovation for ischemic cerebrovascular disease. Helsinki model cut stroke thrombolysis delays to 25 minutes in Melbourne in only 4 months.

Nguyen-Huynh MN. Presentation; Published October American Hospital Association. October Accessed October 11, Critical issues in the evaluation and management of adult patients presenting to the emergency department with suspected pulmonary embolism.

Ann Emerg Med. Wood KE. Major pulmonary embolism: review of a pathophysiologic approach to the golden hour of hemodynamically significant pulmonary embolism. Deep Vein Thrombosis and Pulmonary Embolism. Comprehensive Vascular and Endovascular Surgery. Philadelphia, PA: Elsevier Limited; Accessed March 18, Risk score for intracranial hemorrhage in patients with acute ischemic stroke treated with intravenous tissue-type plasminogen activator.

Symptoms and signs of posterior circulation ischemia in the New England Medical Center posterior circulation registry. Arch Neurol. This video presents an overview of the steps required to diagnose acute ischemic stroke, including brain imaging.

This video provides a demonstration of the appropriate reconstitution, dosing, and administration of Activase for eligible acute ischemic stroke patients. Swab the top of each vial with an alcohol wipe to reduce the risk of contamination. Do not prime the syringe with air. Safely discard the diluent vial according to institutional procedures.

Step 3: Insert the syringe into the stopper on the mg vial of Activase and inject the contents, directing the stream into the lyophilized cake. Safely discard the needle and syringe according to institutional procedures.