Can you drink cranberry juice with coumadin

It is possiblethat the cranberry juice added to theother hypoprothrombinemic effects inthese patients produced an elevatedinternational normalized ratio INR andhemorrhage. While cranberry juice contains salicylicacid, it is unlikely that the salicylic acidwould affect the INR or even platelets.

No definitive studieshave shown cranberry juice can inhibitany metabolic enzyme implicated in themetabolism of warfarin, however.

In astudy of the effects of cranberry juice onflurbiprofen Ansaid metabolism, a single,mL dose of cranberry juice hadno effect on flurbiprofen metabolism. Thus, this study indicates that a singledose of cranberry juice given tohealthy persons does not appear toaffect warfarin metabolism.

Patients takingcranberry juice for its antimicrobial orantioxidant effects will likely be consuminglarger doses. Indeed, the case reportsof enhanced warfarin effect have allnoted chronic consumption of higherdoses of cranberry juice.

Further study isneeded to determine what, if any, dosedependentresponse is observed betweencranberry juice and warfarin. As with other purported warfarin interactions,several case reports suggestthat cranberry juice may enhance theanticoagulant effect of warfarin.

On theother hand, the only prospective trialconducted to date failed to identify aneffect of cranberry juice on CYP2C9activity. Thanks for visiting. Don't miss your FREE gift. Sign up to get tips for living a healthy lifestyle, with ways to fight inflammation and improve cognitive health , plus the latest advances in preventative medicine, diet and exercise , pain relief, blood pressure and cholesterol management, and more.

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